Spatiotemporal omics have provided great new opportunities to systematically understand biological processes. The second International Plant SpatioTemporal Omics Research Conference will be held in Beijing, China, from November 27th-30th, 2025. This conference aims to unite researchers worldwide to share their scientific efforts in spatiotemporal omics in plant research and to discuss the further development of STOC Plant. *STOC Plant 2025 is hosted by Plant Spatiotemporal Omics Consortium (STOC Plant) and organized by BGI Research, Beijing, Southern University of Science and Technology, and GigaScience.